Follow the arithmetic and one habit of commentary collapses. If velocity is nominal output divided by the money stock, then a fall in velocity means the numerator grew more slowly than the denominator, and nothing more. So a sentence like "prices did not rise because the money supply grew but velocity fell" contains no independent information: the second clause is a restatement of the first observation about output, expressed as a ratio. The published series can describe what happened, and it cannot serve as evidence for why, because it has no source data of its own to bring: it is built from the very numbers whose movement it is being offered to explain. Whether the underlying behavior, how readily households and firms part with the money they hold, drives anything is a real economic question. The measured ratio cannot answer it, and an argument that cites a fall in velocity as the reason output grew more slowly than money has restated its observation rather than explained it.
There is a narrower use that is legitimate, and it is bookkeeping rather than explanation. Velocity is the term that connects the quantity of money to the value of transactions, so it is what makes "more money means higher prices" a conditional claim rather than an identity. Money can grow while measured velocity falls, in which case nominal output need not grow at all. That is a statement about the arithmetic relationship between three published series, not a verdict on how monetary policy works, and the pages on monetary policy and inflation are where that debate belongs.
The most useful practical warning concerns M1 velocity across May 2020. The M1 money stock was redefined that month when savings deposits were reclassified into M1, and the Federal Reserve put the resulting increase at approximately $11.2 trillion. Because M1 is the denominator of M1 velocity, an overnight increase in the denominator produces an overnight collapse in the ratio. The series notes for M1 velocity carry the redefinition in their own text: "Beginning May 2020, M1 consists of (1) currency outside the U.S. Treasury, Federal Reserve Banks, and the vaults of depository institutions; (2) demand deposits at commercial banks ...; and (3) other liquid deposits, consisting of OCDs and savings deposits (including money market deposit accounts)." A chart of M1 velocity spanning that date shows a cliff that is a bookkeeping artifact. M2 velocity is not affected, because M2 was unchanged by the reclassification.
Two smaller cautions follow from how the series is built. It is quarterly, because nominal GDP is quarterly, so velocity cannot be read monthly no matter how monthly the money data are. And it is a unitless ratio rather than a percentage or a dollar amount, so a "velocity of 1.2" is not 120 percent of anything; it is output divided by money for that quarter, on that definition of money.